Nueva publicación del CNMT


Se ha publicado un nuevo artículo con el Título:

Molecular Evidence of a Trypanosoma brucei gambiense Sylvatic Cycle in the Human African Trypanosomiasis Foci of Equatorial Guinea

 Carlos Cordon-Obras2, Yasmin Fermin Rodriguez1, Amalia Fernandez-Martinez1, Jorge Cano3, Nicolas Ndong-Mabale4, Policarpo Ncogo-Ada4, Pedro Ndongo Asumu4, Pilar Aparicio1, Miguel Navarro2, Agustin Benito1 and Jean-Mathieu Bart1, 2*

  • 1Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Spain
  • 2Instituto de Parasitologia y Biomedicina Lopez Neyra,, Consejo Superior de Investigacion Cientifica, Spain
  • 3Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, United Kingdom
  • 4Centro de Referencia para el Control de Endemias, Instituto de Salud Carlos III, Equatorial Guinea

...The role of animals as a reservoir of T. b. gambiense is still controversial, but could partly explain maintenance of the infection at hypo-endemic levels. In the present study, we evaluated the presence of T. b. gambiense in wild animals in Equatorial Guinea. The infection rate ranged from 0.8% in the insular focus of Luba to more than 12% in Mbini, a focus with a constant trickle of human cases. The parasite was detected in a wide range of animal species including four species never described previously as putative reservoirs. Our study comes to reinforce the hypothesis that animals may play a role in the persistence of T. b. gambiense transmission, being particularly relevant in low transmission settings. Under these conditions the integration of sustained vector control and medical interventions should be considered to achieve the elimination of Gambiense trypanosomiasis...

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